AgentSkillsCN

model-template

模型模板库——生成 NONMEM 控制流模板。

SKILL.md
--- frontmatter
name: model-template
description: Model Template Library - Generate NONMEM control stream templates

Model Template Library

Usage

code
/model-template
/model-template 1cmt-fo
/model-template 2cmt-fo
/model-template 2cmt-zo
/model-template transit
/model-template tmdd

Available Templates

1-CMT First-Order Absorption (1cmt-fo)

  • •ADVAN2 TRANS2
  • •CL, V, KA parameterization
  • •Combined residual error
  • •Template: templates/nonmem-1cmt-fo.mod

2-CMT First-Order Absorption (2cmt-fo)

  • •ADVAN4 TRANS4
  • •CL, V2, Q, V3, KA parameterization
  • •Combined residual error
  • •Template: templates/nonmem-2cmt-fo.mod

2-CMT Zero-Order Absorption (2cmt-zo)

  • •ADVAN4 TRANS4 with ALAG and D1
  • •Zero-order infusion to depot

Transit Compartment (transit)

  • •Multiple transit compartments for delayed absorption
  • •MTT, NN parameterization

TMDD (tmdd)

  • •Target-mediated drug disposition
  • •QSS or full TMDD model

Protocol

  1. •Ask user which template (if not specified)
  2. •Copy template to new run directory
  3. •Fill in placeholders ([PROJECT_NAME], [RUN_NUMBER], etc.)
  4. •Present for user customization
  5. •Validate control stream syntax